Biomaterials and Scaffolds for Interfacial Tissue Engineering

Timeslot: Thursday, April 12, 2018 - 4:15pm to 6:15pm
Track: Tissue Engineering
Room: Grand Ballroom C


Musculoskeletal tissue interfaces are complex, heterogeneous tissues in which the specific spatial composition is tightly linked to biological function. Biomaterials for interfacial tissue engineering must therefore be designed to guide biomimetic tissue organization to regenerate functional constructs. This session will focus on novel biomaterials-based strategies to regenerate musculoskeletal interfaces with particular attention to approaches to control the spatial organization of chemical and/or physical cues to direct cell and tissue response locally and globally within a scaffold. These include advanced scaffold fabrication, biochemical functionalization, scaffold-cell interactions, physical and structural cues, spatial growth factor control, and stem cell lineage commitment for musculoskeletal tissue interface regeneration.


  • 4:15 p.m. 268. Invited Speaker: Helen Lu, PhD, Columbia University

  • 4:45 p.m. 269. Spatiotemporally controlled transgene expression in hydroxyapatite-doped fibrin scaffolds using high intensity focused ultrasound, A. Moncion(1), J. Harmon(1), Y. Li(1), O. Kripfgans(1), J. Stegemann(1), F. Martín-Saavedra(2), N. Vilaboa(2), R. Franceschi(1), M. Fabiilli*(1); (1)University of Michigan, Ann Arbor, MI, (2)Hospital Universitario La Paz-IdiPAZ, Madrid, Spain

  • 5:00 p.m. 270. Direct Fabrication of Cell-Loaded Nanofibrous Hydrogel Scaffolds Using Reactive Electrospinning, F. Xu*, M. Dodd, H. Sheardown, T. Hoare; McMaster University, Hamilton, ON

  • 5:15 p.m. 271. A Continuous Pore Size Gradient PLLA Scaffold for Osteochondral Regeneration Tested in a Biphasic Bioreactor, R. Gottardi*(1), G. Conoscenti(2), P. Alexander(1), V. La Carrubba(2), V. Brucato(2), R. Tuan(1); (1)University of Pittsburgh, Pittsburgh, PA, (2)Universita` degli Studi di Palermo, Palermo, Italy

  • 5:30 p.m. 272. Dynamic biointerfaces based on sulfonated polyrotaxanes for enhancing osteogenic differentiation, Y. Arisaka*, N. Yui; Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, Tokyo, Japan

  • 5:45 p.m. 273. Manufacturing Gradient Fibers using Magnetically-Assisted Electrospinning for Interfacial Tissue Engineering, R. Tindell, M. Le, A. Gualtieri, J. Holloway*; Arizona State University, Tempe, AZ

  • 6:00 p.m. 274. Triphasic biomaterial for enhanced toughness and regeneration of the osteotendinous junction, R Sun Han Chang*, C Lee, S Rogers, B Harley; University of Illinois at Urbana–Champaign, Urbana, IL

Invited Speaker(s)