Drug Delivery

Timeslot: Wednesday, April 11, 2018 - 1:00pm to 3:00pm
Track: Drug Delivery
Room: Grand Ballroom D


The Drug Delivery SIG session will consider abstracts that fall with the broad areas of therapeutic development, formulation, and application testing. Drug delivery from medical devices, tissue engineering scaffolds/hydrogels, films, microparticles, nanoparticles, environmentally responsive materials, and other types of biomaterial assemblies are all invited. Studies testing drug targeting, drug combinations, and drug/cell combinations are all also welcomed to submit. Drug delivery application areas of interest include but are not limited to regenerative medicine/tissue engineering, cell and tissue transplant, cardiovascular stents and other devices, cancer, microbial infection, and autoimmune diseases.


  • 1:00 p.m. 16. Visceral adipose tissue macrophage-targeted gene delivery for treating obesity-induced type II diabetes, Y Song*, S Yong, H Wee, J Chung, Y Kim; Hanyang University, Seoul, Republic of Korea

  • 1:15 p.m. 17. Tuning Hydrophobe Density and Length in an Anionic Polymer for Enhanced Intracellular Delivery of a CPP-based MAPKAP Kinase II Inhibitor, E. Dailing*, K. Kilchrist, B. Evans, C. Duvall; Vanderbilt University, Nashville, TN

  • 1:30 p.m. 18. Refilling Drug-Eluting Depots through Systemic Administration of Inert Prodrugs, Y. Brudno*(1), B. Kwee(2), N. Joshi(2), M. Aizenberg(3), D. Mooney(2); (1)North Carolina State University, Raleigh, NC, (2)Harvard University, Cambridge, MA, (3)Wyss Institute, Cambridge, MA

  • 1:45 p.m. 19. Influence of Formulation on Cyclodextrin Retention and Drug Delivery for Gastrointestinal Luminal Wound Healing, N. Rohner*(1), S. Merritt(1), S. Zuckerman(1), S. Schomisch(1), J. Marks(2), H. von Recum(1); (1)Case Western Reserve University, Cleveland, OH, (2)University Hospitals Cleveland Medical Center, Cleveland, OH

  • 2:00 p.m. 20. Evaluation of Bone Forming Potential of Simvastatin-containing Polymeric Prodrugs, N Venkatesan*, A Liyanage, J Castro-Núñez, T Asafo-Adjei, T Dziubla, L Cunningham, D Puleo; University of Kentucky, Lexington, KY

  • 2:15 p.m. 21. RhoA knockdown by PgP/siRhoA polyplexes reduces secondary injury in a rat TBI model, C Macks*(1), S Gwak(1), D Jeong(1), M Lynn(2), J Lee(1); (1)Clemson University, Greenville, SC, (2)Greenville Hospital System, Greenville, SC

  • 2:30 p.m. 22. Engineered Controlled Macromolecular Delivery Scaffold for Rotator Cuff Repair, A. Prabhath*(1), V. Vernekar(2), S. Kumbar(2), C. Laurencin(2); (1)University of Connecticut, Storrs, CT, (2)UConn Health, Farmington, CT

  • 2:45 p.m. 23. Development of a Novel Topical Controlled Release System for Otic Drug Delivery, L Bruk*, M Fedorchak; University of Pittsburgh, Pittsburgh, PA