Enzyme-Assisted Biomaterial Fabrication and Modification for Biological Applications

Timeslot: Friday, April 13, 2018 - 1:45pm to 3:45pm
Track: Biomaterials Fabrication and Analysis
Room: 204/205


Enzymes play critical roles in regulating cellular functions and cell-matrix interactions. Due to their substrate specificity and reaction efficiency, enzymatic reactions are increasingly explored for biomaterials fabrication and modification in a myriad of biomedical applications. This symposium will focus on exploiting specific and efficient enzymatic reactions to fabricate and/or modify biomaterials with preferential properties. Emphasis of the symposium will be on the design principles and novel use of enzymes to prepare/modify fibers, films, hydrogels, scaffolds, particles, or other materials with biologically relevant applications.


  • 1:45 p.m. 362. Synthetic B-cells for fusion-mediated dynamic insulin secretion, G Chen*, Z Chen, J Wang, Z Gu; University of North Carolina at Chapel Hill, Raleigh, NC

  • 2:00 p.m. 363. Reversibly stiffened hydrogels via enzyme-mediated peptide ligation, C. Lin, M. Arkenberg, D. Moore*; Indiana University-Purdue University, Indianapolis, IN

  • 2:15 p.m. 364. Enzyme-Mediated Chemical Modifications of Silk Fibroin Towards Advanced Biofunctional Silk Hydrogels, M. McGill*, D. Kaplan; Tufts University, Medford, MA

  • 2:30 p.m. 365. Sustained Release of Antimicrobial Drugs from Graphene Oxide Immobilized Titanium Surfaces for the Enhanced Antibacterial Activity, D. Tran*, T. Hoang Thi, T. Le, K. Park; Ajou University, Suwon, Republic of Korea

  • 2:45 p.m. 366. Engineering Highly Stable Enzyme-Polymer Conjugates: Molecular Dynamics Simulation Study, S. Tu*(1), C. Choudhury(1), S. Collins(2), N. Yadavalli(3), N. Borodinov(1), I. Luzinov(1), S. Minko(3), O. Kuksenok(1); (1)Clemson University, Clemson, SC, (1)Clemson Univerisity, Clemson, SC, (2)Coe College, Cedar Rapids, IA, (3)The University of Georgi

  • 3:00 p.m. 367. Design of Enzymatically Triggered Shape Memory Polymers, J Henderson(1), P Mather(2), S Buffington*(1), C Lee(2); (1)Syracuse University, Syracuse, NY, (2)Bucknell University, Lewisburg, PA

  • 3:15 p.m. 368. Hypoxia-Inducible Hydrogels via Enzyme-Immobilization, B. Hudson*(1), H. Liu(2), C. Dawes(1), C. Lin(1); (1)Indiana University-Purdue University, Indianapolis, IN, (2)Purdue University, West Lafayette, IN

  • 3:30 p.m. 369. Controlled Cell Migration within Cell Selective Hydrogels, E Pashuck*, N Joshi, S Fung, K Kim, J Kohn; Rutgers University, Piscataway, NJ