Harnessing Matrix Biology to Control Cell Fate: A Guest Symposium Sponsored by the American Society for Matrix Biology

Timeslot: Friday, April 13, 2018 - 10:30am to 12:30pm
Track: Wound Healing and Cellular Microenvironment
Room: Grand Ballroom D


Many subfields within the biomaterials community routinely employ the use of extracellular matrix (ECM) based materials for a variety of purposes, including cell and tissue engineering. ASMB members focus on understanding basic biochemical properties of ECM components in addition to characterizing cellular responses to ECM proteins. The goal of this symposium is to facilitate interactions between biomaterial scientists with synergistic communities that focus on ECM biology. This session invites presentations from researchers in the field that describe biochemical and mechanical properties of ECM components, cell-ECM interactions, and application of ECM-based materials to engineered cellular microenvironments.


  • 10:30 a.m. 344. Invited Speaker: Michael Smith, PhD, Boston University

  • 11:00 a.m. 345. Inflammation-Mediated Provisional Matrix Citrullination Leads to Altered Fibroblast Interactions, V Stefanelli*(1), D Chambers(1), V Yeh(2), K Pesson(1), S Choudhury(1), M Torres(1), T Barker(2); (1)Georgia Institute of Technology, Charlottesville, VA, (2)University of Virginia, Charlottesville, VA

  • 11:15 a.m. 346. Breast Cancer Mechanical Background Controls Motility and Metastasis, A Schwartz*, C Hall, S Duquette, S Peyton; University of Massachusetts Amherst, Amherst, MA

  • 11:30 a.m. 347. Boronate-Based Hydrogels with Fast Relaxation Dynamics for 3D Cell Culture, S. Tang*(1), H. Ma(1), P. Lin(2), K. Anseth(1); (1)University of Colorado Boulder, Boulder, CO, (2)National Sun Yat-sen University, Kaohsiung, Taiwan

  • 11:45 a.m. 348. Synthetic Hydrogels for Human Intestinal Organoid Generation and Colonic Wound Repair, R. Cruz-Acuña*(1), M. Quirós(2), A. Farkas(3), P. Dedhia(4), S. Huang(4), D. Siuda(2), V. García-Hernández(2), A. Miller(4), J. Spence(4), A. Nusrat(2), A. García(1); (1)Georgia Institute of Technology, Atlanta, GA, (2)University of Michigan, Ann Arbor, M

  • 12:00 noon 349. Human Cardiomyocyte Ontogenic Responses to Tissue- and Cell-derived Cardiac Extracellular Matrices, A Silva(1), A Kauss(2), J Perez-Bermejo(3), D Swaney(1), D Joy(1), T Hookway(1), D Nascimento(4), P Pinto-do-Ó(4), T McDevitt*(1); (1)Gladstone Institutes, San Francisco, CA, (2)Gladstone Institutes & UCSF, San Francisco, CA, (3)University of California, San Francisco, San Francisco, CA, (4)Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal

  • 12:15 p.m. 350. Force Propagation Through Fibrous Matrices Modulates Endothelial Cell Network Formation, C. Davidson*, W. Wang, V. Chu, B. Baker; University of Michigan, Ann Arbor, MI

Invited Speaker(s)