Immune Engineering

Timeslot: Thursday, April 12, 2018 - 10:30am to 12:30pm
Track: Biomaterials for Immunity and Cancer
Room: 210/211

About

The Immune Engineering SIG is soliciting abstracts that deal with engineered biomaterials for the development of immunotherapeutics and immune microenvironment engineering, to uncover fundamental mechanisms of immunobiology, and for systems immunology.

Abstracts

  • 10:30 a.m. 205. Ex Vivo Immune Organoids to Model Epigenetics and Transcriptional Feedback Loop in Humoral Immunity, A. Singh*(1), W. Beguelin(2), A. Purwada(1), A. Melnick(2); (1)Cornell University, Ithaca, NY, (2)Weill Cornell Medical College of Cornell University, New You, NY

  • 10:45 a.m. 206. Multi-Niche Human Bone Marrow-on-a-Chip for Studying Hematopoietic Stem Cell Dynamics, M. Nelson*(1), A. Krishnan(2), K. Roy(1); (1)Georgia Institute of Technology and Emory University, Atlanta, GA, (2)Georgia Institute of Technology, Atlanta, GA

  • 11:00 a.m. 207. Biomaterial nanoparticles redistribute therapeutic antibodies to lymph node-resident cells to enhance cancer immunotherapy via checkpoint inhibition, D Francis*, A Schudel, N Rohner, S Thomas; Georgia Institute of Technology, Atlanta, GA

  • 11:15 a.m. 208. Combination Nanovaccine Induces Rapid and Long-lived Protective Immunity against Yersinia pestis, S Kelly*(1), D Wagner-Muniz(1), N Peroutka-Bigus(1), T Dubensky(2), B Bellaire(1), M Wannemuehler(1), B Narasimhan(1); (1)Iowa State University, Ames, IA, (2)Aduro Biotech, Berkeley, CA

  • 11:30 a.m. 209. An antigen-specific microparticle system blocks experimental autoimmune encephalomyelitis, J. Stewart*, J. Cho, T. Drashansky, M. Brusko, A. Zuniga, K. Lorentsen, D. Avram, B. Keselowsky; University of Florida, Gainesville, FL

  • 11:45 a.m. 210. Harnessing Long-Term Release to Produce Robust Long-term Immunity, E Appel*, G Agmon, A Yu; Stanford University, Stanford, CA

  • 12:00 noon 211. Targeted extracellular delivery of Indoleamine 2,3-Dioxygenase via fusion with Galectin 3 ameliorates inflammation in vitro and in vivo, E Bracho-Sanchez*, K Koenders, A Restuccia, M Fettis, M Wallet, F Rocha, S Wallet, G Hudalla, B Keselowsky; University of Florida, Gainesville, FL

  • 12:15 p.m. 212. Characterization of the Immune Response to Biomaterial-Mediated Infection Following Trauma, C. Vantucci*(1), H. Ahn(2), M. Schenker(2), P. Pradhan(1), K. Roy(1), R. Guldberg(1), N. Willett(2); (1)Georgia Institute of Technology, Atlanta, GA, (2)Emory University, Atlanta, GA