Nano Drug Delivery

Timeslot: Thursday, April 12, 2018 - 10:30am to 12:30pm
Track: Drug Delivery
Room: Grand Ballroom D


The Drug Delivery SIG session will consider abstracts that fall with the broad areas of therapeutic development, formulation, and application testing. Drug delivery from medical devices, tissue engineering scaffolds/hydrogels, films, microparticles, nanoparticles, environmentally responsive materials, and other types of biomaterial assemblies are all invited. Studies testing drug targeting, drug combinations, and drug/cell combinations are all also welcomed to submit. Drug delivery application areas of interest include but are not limited to regenerative medicine/tissue engineering, cell and tissue transplant, cardiovascular stents and other devices, cancer, microbial infection, and autoimmune diseases.


  • 10:30 a.m. 182. S-nitrosated poly(propylene sulfide) nanoparticles for enhanced nitric oxide delivery to lymphatic tissues and lymph node-resident cells, A Schudel*, L Sestito, S Thomas; Georgia Institute of Technology, Atlanta, GA

  • 10:45 a.m. 183. Supramolecular PEGylation as an Innovative Approach to Biopharmaceutical Formulation and Delivery, E Appel*, C Maikawa, G Agmon; Stanford University, Stanford, CA

  • 11:00 a.m. 184. Galectin-8 Imaging Demonstrates Endosomal Disruption by Nanocarrier and Predicts Biologic Drug Intracellular Bioavailability, K. Kilchrist*, S. Dimobi, T. Werfel, E. Dailing, M. Jackson, C. Duvall; Vanderbilt University, Nashville, TN

  • 11:15 a.m. 185. Efficient Gene Editing Using a Bioegradable Nanocapsule Containing Cas9 Ribonucleoprotein, A. Abdeen*, G. Chen, P. Shahi, R. Xie, B. Pattnaik, S. Gong, K. Saha; University of Wisconsin-Madison, Madison, WI

  • 11:30 a.m. 186. Optimization and comparison of CD4-targeting lipid-polymer hybrid nanoparticles using different binding ligands, S. Cao*(1), Y. Jiang(1), C. Levy(1), S. Hughes(1), H. Zhang(1), F. Hladik(2); (1)University of Washington, Seattle, WA, (2)Fred Hutchinson Cancer Research Center, and University of Washington, Seattle, WA

  • 11:45 a.m. 187. Engineered Extracellular Vesicles with Synthetic Lipids via Membrane Fusion to Establish Efficient and Targeted Drug and Gene Delivery, Y. Jhan*, D. Moore, S. Arun Kumar, C. Bishop; Texas A&M University, College Station, TX

  • 12:00 noon 188. Development of Layer-by-Layer Assembled Nanoshells for Intracellular miR-34a Delivery, R. Goyal, E. Day*; University of Delaware, Newark, DE

  • 12:15 p.m. 189. NIR Triggered Photodynamic/Chemotherapy in Combination with Immunotherapy by Using Cascade Upconversion Nanoparticles for Elimination of Primary Tumor and Remission of Metastasis, J. Chen*; Institute of High Energy Physics, Chinese Academy of Sciences, Beijing, China