Rapid Fire: Biomaterials and Scaffolds for Interfacial Tissue Engineering

Timeslot: Wednesday, April 11, 2018 - 3:15pm to 4:45pm
Track: Tissue Engineering
Room: Grand Ballroom D


Musculoskeletal tissue interfaces are complex, heterogeneous tissues in which the specific spatial composition is tightly linked to biological function. Biomaterials for interfacial tissue engineering must therefore be designed to guide biomimetic tissue organization to regenerate functional constructs. This session will focus on novel biomaterials-based strategies to regenerate musculoskeletal interfaces with particular attention to approaches to control the spatial organization of chemical and/or physical cues to direct cell and tissue response locally and globally within a scaffold. These include advanced scaffold fabrication, biochemical functionalization, scaffold-cell interactions, physical and structural cues, spatial growth factor control, and stem cell lineage commitment for musculoskeletal tissue interface regeneration.


  • 3:15 p.m. 78. Biomimetic Hydrogel Supports the Development of Murine Primary Ovarian Follicles Co-cultured with Human Adipose Derived Stem Cells, C. Tomaszewski*, H. Zhou, E. Constance, A. Shikanov; University of Michigan, Ann Arbor, MI

  • 3:20 p.m. 79. Micropatterned graphene-incorporated conductive hydrogels produced by Femtosecond laser ablation for potential skeletal muscle tissue engineering applications, J. Park*, J. Lee; Gwangju Institute Science and Technology (GIST), Gwangju, Republic of Korea

  • 3:25 p.m. 80. 3D Printed Bioactive Ceramic Scaffolds Coated with Dipyridamole Regenerate Vascularized Bone Without Suture Fusion in Alveolar Cleft Defects, C. Lopez*(1), F. Gendy(1), L. Witek(1), S. Maliha(2), R. Flores(2), L. Cavdar(1), A. Torroni(2), J. Bekisz(2), B. Cronstein(2), P. Coelho(1); (1)New York University, New York, NY, (2)NYU School of Medicine, New York, NY

  • 3:30 p.m. 81. MSC Spheroid Laden Amorphous Silica Fiber Matrix for Osteochondral Regeneration, H Kim*(1), M Hu(2), S Nukavarapu(2); (1)University of Connecticut, Storrs, CT, (2)University of Connecticut Health, Farmington, CT

  • 3:35 p.m. 82. Extracellular Matrix Paper (ECM-paper) for Construction of Multi-layered Blood vessel wall tissues, H. Nakatsuji*, M. Matsusaki; Graduate school of engineering, Osaka University, Suita, Japan

  • 3:45 p.m. 83. Bioinspired Fibrin Microthreads Deliver FGF2 to Guide in vitro Skeletal Muscle and Endothelial Cell Function, M Carnes*, K Castellano, G Pins; Worcester Polytechnic Institute, Worcester, MA

  • 3:50 p.m. 84. PCL-Chitosan-Magnesium Oxide Based Composite Nanofibers for Tissue Engineering Applications, U. Adhikari*; North Carolina A&T State University, Greensboro, NC

  • 3:55 p.m. 85. Electrospun Poly(?-caprolactone) Nanofiber Shish Kebabs Mimic Mineralized Collagen Fibrils in Bone, T Yu*, M Marcolongo, C Li; Drexel University, Philadelphia, PA

  • 4:00 p.m. 86. Opposing Mineral and Protein Gradients in a Nanofiber Scaffold Promotes Spatial Cellular Response, S Patel*(1), K Schutt(1), D Qu(1), A Deymier(1), S Doty(2), S Thomopoulos(1), H Lu(1); (1)Columbia University, New York, NY, (2)Hospital for Special Surgery, New York, NY

  • 4:05 p.m. 87. GermanyGeneration of Rapid In Situ Forming Channels within Soft Biomaterials via Biodegradable Fiber Porogens, A Chen*, D Puleo; University of Kentucky, Lexington, KY

  • 4:15 p.m. 88. Biologically Inspired Osteoinductive Scaffolds with Drug Eluting Spheres, E. Mondragon*(1), M. Cowdin(1), F. Taraballi(2), E. Tasciotti(2), R. Kaunas(1); (1)Texas A&M University, College Station, TX, (2)Houston Methodist, Houston, TX

  • 4:20 p.m. 89. A High-Throughput Microchannel Scaffold Fabrication Technique, D Shahriari*, Y Fink, P Anikeeva; Massachusetts Institute of Technology, Cambridge, MA

  • 4:25 p.m. 90. Electrochemical Manipulation of a Cell Monolayer Supported by a Biodegradable Polymeric Nanosheet for Cell Transplantation Therapy, H. Kaji*, J. Suzuki, N. Nagai, T. Abe; Tohoku University, Sendai, Japan

  • 4:30 p.m. 91. Treatment of Osteoarthritis Using Macrophage-Targeting Hyaluronic Acid Microscaffolds, S Li, J Zhou, A Hakamivala, Y Huang, W Cong, J Borrelli, L Tang*; University of Texas at Arlington, Arlington, TX

  • 4:35 p.m. 92. 3D Printing Spatially Organized Scaffolds for Osteochondral Interface Regeneration, H. Busari*, P. Schwarzenberg, P. Camacho, K. Hudson, H. Dailey, L. Chow; Lehigh University, Bethlehem, PA