Rapid Fire: Drug Delivery

Timeslot: Wednesday, April 11, 2018 - 3:15pm to 4:45pm
Track: Drug Delivery
Room: Grand Ballroom B


The Drug Delivery SIG session will consider abstracts that fall with the broad areas of therapeutic development, formulation, and application testing. Drug delivery from medical devices, tissue engineering scaffolds/hydrogels, films, microparticles, nanoparticles, environmentally responsive materials, and other types of biomaterial assemblies are all invited. Studies testing drug targeting, drug combinations, and drug/cell combinations are all also welcomed to submit. Drug delivery application areas of interest include but are not limited to regenerative medicine/tissue engineering, cell and tissue transplant, cardiovascular stents and other devices, cancer, microbial infection, and autoimmune diseases.


  • Nanoparticles

  • 3:15 p.m. 93. Intestinal Organoids Containing PLGA Nanoparticles for the Treatment of Inflammatory Bowel Diseases, Z. Davoudi*, N. Peroutka-Bigus, B. Bellaire, M. Wannemuehler, B. Narasimhan, Q. Wang; Iowa State University, Ames, IA

  • 3:20 p.m. 94. Modular Nanoparticle Scaffolds for Tunable Drug Delivery, K Peuler*, C Lin; Indiana University Purdue University Indianapolis, Indianapolis, IN

  • 3:25 p.m. 95. EPITOPE-FUNCTIONALIZED NANOPARTICLES FOR ENTRAPMENT OF AUTISM AUTO-ANTIBODY, A Bolandparvaz*(1), E Edmiston(2), K Alvarez(1), J Van De Water(1), J Lewis(1); (1)UC Davis, Davis, CA, (2)Blueprint Research, San Francisco, CA

  • 3:30 p.m. 96. Tailoring Swelling pH of Poly(Sialic Acid) Micelles Based on Core Hydrophobicity, G Pawlish*(1), N Comolli(2), K Spivack(2); (1)Temple University, Philadelphia, PA, (2)Villanova University, Villanova, PA

  • 3:35 p.m. 97. Chitosan/Poly(lactide) Drug-Loaded Nanoparticles for Delivery of Therapeutic Compounds, S. DeVeaux*, C. Gomillion; University of Georgia, Athens, GA

  • Cancer

  • 3:45 p.m. 98. Leukocytes as Mobile Carriers of Anti-Cancer Therapeutics via Bispecific Liposomes, Z Zhang*, D Liu, N Ortiz-Otero, T Cao, M King; Vanderbilt University, Nashville, TN

  • 3:50 p.m. 99. A Poly (Lactic-co-glycolic Acid)-based Phase-separating Platform for Controlling the Kinetics of Combinatorial Therapeutics in Ovarian Cancer, S Arun Kumar*, W Souery, Y Jhan, C Bishop; Texas A&M University, College Station, TX

  • 3:55 p.m. 100. Folic Acid Modified Halloysite Nanotubes with Tumor Targeting Capability, Y. Luo*, D. Mills; Louisiana Tech University, Ruston, LA

  • 4:00 p.m. 101. Silk Carriers for Local Delivery of Cisplatin: In Vitro Release Kinetics, B. Yavuz*(1), K. Harrington(1), J. Coburn(2), B. Chiu(3), D. Kaplan(1); (1)Tufts University, Medford, MA, (2)Worcester Polytechnic Institute, Worchester, MA, (3)University of Illinois at Chicago, Chicago, IL

  • 4:05 p.m. 102. Methacrylation of Chondroitin Sulfate for Drug Delivery Applications, K. Ornell*, J. Coburn, N. Phan, W. Linthicum, D. Lozada; Worcester Polytechnic Institute, Worcester, MA

  • Tissue Engineering

  • 4:15 p.m. 103. Biodegradable simvastatin-containing polymeric prodrugs with improved drug release and their application as porous scaffolds for tissue engineering, A Liyanage*, N Venkatesan, D Puleo; University of Kentucky, Lexington, KY

  • 4:20 p.m. 104. Synthesis and characterization of polyethylene (PEG) incorporated hyaluronic acid hydrogels for tissue engineering, J Kim, J Kim*; Hongik University, Sejong, Republic of Korea

  • 4:25 p.m. 105. Sequential Delivery of Ketoprofen and Captopril from a Multilayered Poly(?-amino ester) System for Muscle Repair, N Venkatesan*, D Puleo; University of Kentucky, Lexington, KY

  • 4:30 p.m. 106. Multiple growth factor loading strategy affects spatiotemporal release from heparin microparticles, R. Subbiah*, L. Krishnan, R. Guldberg; Georgia Institute of Technology, Atlanta, GA

  • 4:35 p.m. 107. Development of a bi-modal, in situ crosslinking method to achieve multi-factor release from electrospun gelatin, A Kishan*(1), T Walker(2), N Sears(1), T Wilems(2), E Cosgriff-Hernandez(2); (1)Texas A&M University, Houston, TX, (2)University of Texas, Austin, TX