Supramolecular Design of Network Biomaterials

Timeslot: Saturday, April 14, 2018 - 10:15am to 12:15pm
Track: Biomaterials Fabrication and Analysis
Room: 206/207


The preparation of biomaterials using rationally designed motifs rooted in supramolecular chemistry (i.e., “chemistry beyond the molecule”) affords properties that are reversible, highly tunable, and dynamic, and as such has become an exciting new direction in the field of engineered biomaterials. The reliance on specific, noncovalent interactions affords opportunities in developing materials with “smart” functionality and activity that can be tuned in response to disease or application, and as injectable surrogate matrices for cells. Moreover, conserving the specific supramolecular motif realizes a modular approach to customize a biomaterial in a patient or disease specific way. These efforts have resulted in a suite of new and highly functional network biomaterials for applications in stem cell biology, regenerative medicine, tissue engineering, and drug delivery. In each case, unique features rooted in supramolecular design give rise to important emergent properties.


  • 10:15 a.m. 418. Adaptable Biomaterials for Expansion and Transplantation of Stem Cells, C. Madl, B. LeSavage, R. Dewi, S. Heilshorn*; Stanford University, Stanford, CA

  • 10:45 a.m. 419. Tailoring supramolecular guest-host hydrogel properties with covalent double networks, C. Loebel*(1), A. Ayoub(2), J. Galarraga(1), O. Kossover(2), H. Simaan-Yameen(2), D. Seliktar(2), J. Burdick(1); (1)University of Pennsylvania, Philadelphia, PA, (2)Technion – Israel Institute of Technology, Haifa, Israel

  • 11:00 a.m. 420. Supramolecular Vesicles Transitioned from Coacervates Composed of Recombinant Fusion Protein Complexes, Y Jang*, M Hsieh, S Guo, M Grover, J Champion; Georgia Institute of Technology, Atlanta, GA

  • 11:15 a.m. 421. WITHDRAWN

  • 11:30 a.m. 422. Photolymerized Dynamic Hydrogels with Tunable Viscoelastic Properties Through Thioester Exchange, B. Carberry*(1), T. Brown(1), B. Worrell(1), O. Dudaryeva(2), M. Mcbride(1), C. Bowman(1), K. Anseth(1); (1)University of Colorado at Boulder, Boulder, CO, (2)Institute for Complex Molecular Systems, Eindhoven, Netherlands

  • 11:45 a.m. 423. A Thermo-Responsive Citrate-based Macromolecule for Transarterial Embolotherapy, S. Ramachandra*(1), J. Yang(1), S. Lee(2), G. Ameer(1); (1)Northwestern University, Evanston, IL, (2)University of Chicago, Chicago, IL

  • 12:00 noon 424. Supramolecular peptide and protein matrices for prostate cancer organoid culture, K Hainline*(1), F Gu(1), D Vander Griend(2), J Collier(1); (1)Duke University, Durham, NC, (2)University of Chicago, Chicago, IL

Invited Speaker(s)