Supramolecular Nanomaterials for Drug Delivery, Imaging, and Immunoengineering 2

Timeslot: Friday, April 13, 2018 - 1:45pm to 3:45pm
Track: Drug Delivery
Room: Grand Ballroom D


Due to the versatility and diversity of their materials properties, a wide range of biomedical applications have emerged in recent years using supramolecular nanomaterials. The bottom-up approach to designing functional objects at the nanoscale has been used to develop individual nanoparticles or to produce highly oriented complexes for a growing number of applications including drug delivery, imaging, theranostics, vaccines, and cancer immunotherapy. In addition, there are exciting opportunities for local therapeutic modulation. This session highlights recent advances in nanomaterials design aimed to enhance the in vivo delivery of therapeutic or imaging payloads for a variety of diseases including those affecting the skin, gastrointestinal and respiratory tracts, cardiovascular system, cancer, and other diseased tissues.


  • 1:45 p.m. 378. Supramolecular tools for modulating the morphology of self-assembled helical peptide nanofibers, C Fries*, J Collier, Y Wu, M Wolf; Duke University, Durham, NC

  • 2:00 p.m. 379. Dynamic light scattering of bottlebrush polymers, A Kriete*, K Prudnikova, M Marcolongo; Drexel University, Philadelphia, PA

  • 2:15 p.m. 380. Optimizing Mannose Conjugation to Polymeric Nanoparticles for Targeted Delivery to Tumor Associated Macrophages in Breast Cancer, E. Glass*, S. Masjedi, S. Dudzinski, T. Giorgio; Vanderbilt University, Nashville, TN

  • 2:30 p.m. 381. Multiarm Avidin Nanoconstruct as a Cationic Carrier for Intra-cartilage Drug Delivery, A Vedadghavami, S Mehta, A Bajpayee*, S Bhakta; Northeastern University, Boston, MA

  • 2:45 p.m. 382. Biomimetic peptide display from a polymeric nanoparticle surface for dual functionality to target and treat cancer, J. Green*(1), J. Kim(1), E. Bressler(2), R. Shmueli(1), A. Mirando(1), H. Bazzazi(1), E. Lee(1), A. Popel(1), N. Pandey(1); (1)Johns Hopkins University, Baltimore, MD, (2)AsclepiX Therapeutics, Baltimore, MD

  • 3:00 p.m. 383. Subconjunctival delivery of nanoparticles for safe and efficient treatment of corneal allograft rejection, Q. Xu*(1), M. Chen(2), Q. Pan(2), W. Stark(2), J. Hanes(2); (1)Virginia Commonwealth University, Richmond, VA, (2)Johns Hopkins University, Baltimore, MD

  • 3:15 p.m. 384. Aggregation Behavior of Elastin-Like Polypeptide Copolymers, A. Engel*, J. Cobb, A. Janorkar; Univ. of Mississippi Med Center, Jackson, MS

  • 3:30 p.m. 385. Immunomodulatory Vasoactive Intestinal Peptide Amphiphile Micelles, R. Zhang*, C. Leeper, X. Wang, G. Seim, B. Ulery; University of Missouri, Columbia, MO