Therapeutic Strategies for the Treatment of Infectious Diseases

Timeslot: Thursday, April 12, 2018 - 4:15pm to 6:15pm
Track: Biomaterials for Immunity and Cancer
Room: 210/211

About

Greater than 25% of deaths worldwide are caused by infectious diseases. Rising drug resistance and lack in development of new classes of therapeutics have made it increasingly difficult to treat infections. There is a pressing need to engineer advanced antimicrobial therapeutics, delivery systems, and diagnostics that can rapidly and effectively treat and detect infections, while helping to control the spread of resistance. This session will focus on recent advances spanning industry and academia in novel therapeutic strategies for the treatment of bacterial, fungal, viral, and biofilm associated infections. Topics of interest include, but are not limited to: antimicrobial surfaces and device coatings, novel antimicrobial molecules and macromolecules, antimicrobial nano- and micro-particles, and triggered, targeted, and responsive antimicrobial delivery systems. Given the critical importance of detecting infectious agents prior to treating them, new diagnostic technologies for infectious agents are also of interest.

Abstracts

  • 4:15 p.m. 298. Multifunctional polymeric wound dressing materials: combating drug-resistance, J. Lundin*(1), C. McGann(1), L. Estrella(1), E. Cosgriff-Hernandez(2), J. Wynne(1); (1)Naval Research Laboratory, Washington, DC, (2)University of Texas at Austin, Austin, TX

  • 4:30 p.m. 299. Lipid-Coated Mesoporous Silica Nanoparticles for Antiviral Delivery to Inhibit Encephalitic Alphavirus Infection, T. Rinker*(1), A. LaBauve(1), A. Noureddine(2), C. Brinker(2), D. Sasaki(1), O. Negrete(1); (1)Sandia National Laboratories, Livermore, CA, (2)University of New Mexico, Albuquerque, NM

  • 4:45 p.m. 300. Combating Fungal Infections Using Responsive Hydrogels for Drug Delivery, N. Vera-Gonzalez*, A. Shukla; Brown University, Providence, RI

  • 5:00 p.m. 301. WITHDRAWN

  • 5:15 p.m. 302. Preventing S. aureus Biofilm Formation on Titanium Surfaces by the Release of Antimicrobial β peptides from Polyelectrolyte Multilayer Films, A Rodríguez López*, M Lee, D Lynn, S Palecek; University of Wisconsin, Madison, WI

  • 5:30 p.m. 303. Toward creation of poly(methyl methacrylate) bone cement which can be refilled with antibiotics after implantation, E. Cyphert*(1), S. Hurley(2), C. Lu(1), G. Learn(1), H. von Recum(1); (1)Case Western Reserve University, Cleveland, OH, (2)Fordham University, Bronx, NY

  • 5:45 p.m. 304. Anti-Biofilm Efficacy of Nitric Oxide-Releasing Alginates against Respiratory Pathogens, M Ahonen*, M Schoenfisch; University of North Carolina at Chapel Hill, Chapel Hill, NC

  • 6:00 p.m. 305. On-Demand Pressure-Driven Molecular Release for Active Anti-oxidization, Y. Seo*(1), J. Leong(1), J. Teo(1), J. Mitchell(1), M. Gillette(1), B. Han(2), J. Lee(3), H. Kong(4); (1)University of Illinois at Urbana-Champaign, Urbana, IL, (2)Purdue University, West Lafayette, IN, (3)Chung-Ang University, Seoul, Republic of Korea, (4)Department of Chemical and Biomolecular Engineering, Department of Bioengineering, Institute for Genomic Biology, Urbana, IL